Nanoparticles in Biotechnology, Drug Development and Drug Delivery

February 22, 2013

In the last decade, the science of nanoparticles has made major advances in particle-type production and in nanoparticle application in all areas of the life sciences. The most rapid advances have been made in the application of nanoparticles in drug research and development, drug product formulation, and development of novel drug-delivery systems using nanoparticle carriers.

The development of nanoparticles and their rapid incorporation into the research and development, formulation, and production of drug products has given rise to the need for rapid and accurate analytical instrumentation that is necessary for determining the size and characteristics of particle materials in the nanometer-size range.

Nanoparticles used in the life sciences and biomedical applications are considered to be in the range of 10 to 100 nanometers in diameter. Developing particles from various starting materials that remain stable in this size range has become one of the fastest-growing and most potentially useful emerging technologies of the last several decades.

Both particle size and shape are important in the life sciences because the particle properties of biopharmaceutical products can affect a drug product in two ways – size and shape, both of which can have influences on drug performance or efficacy in the body.

A major challenge of current drug therapy is that the body does not absorb the entire drug dose given to a patient. By using nanoparticle delivery systems, scientists can ensure drugs are properly delivered to specific areas in the body with greater precision and not distributed throughout the body. Drugs can be formulated and included in nanoparticles in such a way that the active ingredient can better permeate cell membranes, thus potentially reducing the required dose.

Two forms of nanoparticles – nanocarriers and nanocrystals – currently are used to deliver cosmetic components absorbed through the skin. A number of FDA-approved drugs are delivered using one form of nanoparticle – the liposome. Several nanoparticle-related drug-delivery systems are in the pipeline of a number of major pharmaceutical companies. Clinical trials are in progress on some of these developments. There is potential in this technology for the successful development and application of future nanotech products to diagnose and treat various diseases.

Two of the most active areas of product development are drug-delivery systems and in vivo imaging. In the pharmaceutical industry, nanoparticles are aiding product reformulation to increase bioavailability of a drug. Nanoparticles also hold promise in reducing the toxicity and side effects of existing drugs.

The methods for producing nanoparticles vary depending on the starting substrate materials and the size particle desired as an end product. This report will provide an overview of various production methods and indicate new advances in the production area.

The above is an extract from the BCC Research report, Nanoparticles in Biotechnology, Drug Development and Drug Delivery (BIO113A). To download the complimentary first chapter, please click here.


Global consumption of nanocomposites to grow to $2.4 billion by 2016

March 21, 2012

Global consumption of nanocomposites was an estimated 118,768 metric tons with a value of over $800 million in 2010. In 2011, the market should reach 138,389 metric tons and $920 million. By 2016, the market should amount to 333,043 metric tons and $2.4 billion, a five year compound annual growth rate (CAGR) of 19.2% in unit terms and 20.9% in value terms.

Learn about the global market for nanocomposites with the greatest commercial potential in the near to mid-term (i.e., 2011 to 2016). Also learn about the nanocomposites that are in commercial use or under development, their associated technologies, and applications. Patent analysis and company profiles are provided as well…

Use this report to:

  • Learn about emerging nanocomposite technologies and applications, along with a realistic assessment of their commercial potential
  • Identify segments of the nanocomposite market with the greatest commercial potential in the near to mid-term (from 2011 to 2016) future
  • Evaluate present consumption and future demand in these nanocomposite market segments
  • Understand the challenges that must be overcome for each market segment to realize its potential, and to estimate the segment’s probability of successful commercialization.

To provide further information about this report we offer a Complimentary Introduction, available from our Website. To download, simply click here, go to the Table of Contents tab, add the complimentary introduction to your cart, and confirm your order.

GLOBAL CONSUMPTION OF NANOCOMPOSITES, 2010-2016
($ MILLIONS)
 GLOBAL CONSUMPTION OF NANOCOMPOSITES, 2010-2016
Source : BCC Research

Nanotechnology Medical Market Could Double Worth by 2013

September 26, 2008

In just five years, the global market for nanomedical technology could more than double its revenue to $3.8 billion. The market also has the potential to explode to $9.4 billion in 2018. These figures come from a study by BCC Research (Wellesley, MA).

The report, called Global Markets for Nanoscale Materials and Devices, separates the market into nano­particles, other nanostructure materials, and nanotools or nanodevices. In 2007, these applications generated $1.7 billion.¹

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¹Maria Fontanazza
Medical Device & Diagnostic Industry

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Growing Role of Nanotechnology in Medical Devices

August 13, 2008

To the surprise of no one, the med-tech industry is finding that there is, still, plenty of room at the bottom, to paraphrase physicist and nanotechnology pioneer Richard Feynman. The global medical market for nanotechnology applications accounted for approximately US$1.7 billion in 2007. The vast majority of this revenue–nearly 90%–was generated by pharmaceutical applications. In the years ahead, however, nanotechnology applications in the medical device arena are forecast to surge, while its use in drug-related activities contracts. Those are some of the findings of a report titled Global Medical Markets for Nanoscale Materials and Devices.

BCC Research, which will issue the report this month, predicts that the use of nanotech-related materials, tools, and devices will attain a compound annual growth rate between 14.9% and 19.9% by 2018, potentially generating US$9.4 billion in revenue. By that time, the report predicts that pharma will account for 51% of the medical share of nanotech applications, whereas medical devices and medical research may account for as much as 20% each.¹

¹MedTech Insider; Norbert Sparrow

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A Brief Nanoparticle Growth Forecast

April 28, 2008

A market research report titled “Nanostructured materials for the biomedical, pharmaceutical, and cosmetic markets,” from BCC Research, says that the global market for nanoparticles for these applications was worth $204.6 million last year, with that number expected to reach $684.4 million by 2012.¹

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¹Healthcare Packaging, healthcarepackaging.com

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